Unknown

Dataset Information

0

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations.


ABSTRACT: Thirty insertion/deletion loci were utilized to study the genetic diversities of 125 bloodstain samples collected from Bai group in Yunnan Dali region, China. The observed heterozygosity and expected heterozygosity of the 30 loci ranged from 0.1520 to 0.5680, and 0.1927 to 0.4997, respectively. No deviations from Hardy-Weinberg equilibrium tests after Bonferroni correction were found at all 30 loci in Bai group. The cumulative probability of exclusion and combined discrimination power were 0.9859 and 0.9999999999887, respectively, which indicated the 30 loci could be used as complementary genetic markers for paternity testing and were qualified for personal identification in forensic cases. We found the studied Bai group had close relationships with Tibetan, Yi and Han groups from China by the population structure, principal component analysis, population differentiations, and phylogenetic reconstruction studies. Even so, for a better understanding of Bai ethnicity's genetic milieu, DNA genotyping at various genetic markers is necessary in future studies.

SUBMITTER: Yang CH 

PROVIDER: S-EPMC5503634 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Genetic variation and forensic efficiency of autosomal insertion/deletion polymorphisms in Chinese Bai ethnic group: phylogenetic analysis to other populations.

Yang Chun-Hua CH   Yin Cai-Yong CY   Shen Chun-Mei CM   Guo Yu-Xin YX   Dong Qian Q   Yan Jiang-Wei JW   Wang Hong-Dan HD   Zhang Yu-Dang YD   Meng Hao-Tian HT   Jin Rui R   Chen Feng F   Zhu Bo-Feng BF  

Oncotarget 20170601 24


Thirty insertion/deletion loci were utilized to study the genetic diversities of 125 bloodstain samples collected from Bai group in Yunnan Dali region, China. The observed heterozygosity and expected heterozygosity of the 30 loci ranged from 0.1520 to 0.5680, and 0.1927 to 0.4997, respectively. No deviations from Hardy-Weinberg equilibrium tests after Bonferroni correction were found at all 30 loci in Bai group. The cumulative probability of exclusion and combined discrimination power were 0.985  ...[more]

Similar Datasets

| S-EPMC9245983 | biostudies-literature
| S-EPMC7005628 | biostudies-literature
| S-EPMC9245971 | biostudies-literature
| S-EPMC7196475 | biostudies-literature
| S-EPMC3909073 | biostudies-literature
| S-EPMC6501771 | biostudies-literature
| S-EPMC6732286 | biostudies-literature
| S-EPMC6030347 | biostudies-literature
| S-EPMC378575 | biostudies-literature
| S-EPMC7205039 | biostudies-literature