Ontology highlight
ABSTRACT:
SUBMITTER: Hillion M
PROVIDER: S-EPMC5504048 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Hillion Melanie M Imber Marcel M Pedre Brandán B Bernhardt Jörg J Saleh Malek M Loi Vu Van VV Maaß Sandra S Becher Dörte D Astolfi Rosado Leonardo L Adrian Lorenz L Weise Christoph C Hell Rüdiger R Wirtz Markus M Messens Joris J Antelmann Haike H
Scientific reports 20170710 1
Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes and functions in post-translational thiol-modification by protein S-mycothiolation as emerging thiol-protection and redox-regulatory mechanism. Here, we have used shotgun-proteomics to identify 26 S-mycothiolated proteins in the pathogen Corynebacterium diphtheriae DSM43989 under hypochlorite stress that are involved in energy metabolism, amino acid and nucleotide biosynthesis, antioxidant functions and translation. T ...[more]