Ontology highlight
ABSTRACT:
SUBMITTER: Vajen T
PROVIDER: S-EPMC5505004 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Vajen Tanja T Benedikter Birke J BJ Heinzmann Alexandra C A ACA Vasina Elena M EM Henskens Yvonne Y Parsons Martin M Maguire Patricia B PB Stassen Frank R FR Heemskerk Johan W M JWM Schurgers Leon J LJ Koenen Rory R RR
Journal of extracellular vesicles 20170516 1
Extracellular vesicles (EVs) are mediators of cell communication during health and disease, and abundantly released by platelets upon activation or during ageing. Platelet EVs exert modulatory effects on immune and vascular cells. Platelet EVs may modulate the function of vascular smooth muscle cells (SMC). Platelet EVs were isolated from platelet-rich plasma and incubated with SMC in order to assess binding, proliferation, migration and pro-inflammatory phenotype of the cells. Platelet EVs firm ...[more]