Ontology highlight
ABSTRACT:
SUBMITTER: Kalimuthu S
PROVIDER: S-EPMC5505027 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Kalimuthu Senthilkumar S Oh Ji Min JM Gangadaran Prakash P Zhu Liya L Lee Ho Won HW Rajendran Ramya Lakshmi RL Baek Se Hwan SH Jeon Yong Hyun YH Jeong Shin Young SY Lee Sang-Woo SW Lee Jaetae J Ahn Byeong-Cheol BC
Stem cells international 20170627
CXCR4, the stromal cell-derived factor-1 receptor, plays an important role in the migration of hematopoietic progenitor/stem cells to injured and inflamed areas. Noninvasive cell tracking methods could be useful for monitoring cell fate. Therefore, in this study, we evaluated the efficacy of an intravenous infusion of genetically engineered mesenchymal stem cells (MSCs) overexpressing CXC chemokine receptor 4 (CXCR4) to home to the tumor, by optical imaging. We constructed a retroviral vector co ...[more]