Ontology highlight
ABSTRACT:
SUBMITTER: Fernandez-Rebollo E
PROVIDER: S-EPMC5506010 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Fernandez-Rebollo Eduardo E Mentrup Birgit B Ebert Regina R Franzen Julia J Abagnale Giulio G Sieben Torsten T Ostrowska Alina A Hoffmann Per P Roux Pierre-François PF Rath Björn B Goodhardt Michele M Lemaitre Jean-Marc JM Bischof Oliver O Jakob Franz F Wagner Wolfgang W
Scientific reports 20170711 1
Culture medium of mesenchymal stromal cells (MSCs) is usually supplemented with either human platelet lysate (HPL) or fetal calf serum (FCS). Many studies have demonstrated that proliferation and cellular morphology are affected by these supplements - it is therefore important to determine if they favor outgrowth of different subpopulations and thereby impact on the heterogeneous composition of MSCs. We have isolated and expanded human bone marrow-derived MSCs in parallel with HPL or FCS and dem ...[more]