Ontology highlight
ABSTRACT:
SUBMITTER: Hayashi Y
PROVIDER: S-EPMC5507494 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Hayashi Yuichiro Y Yawata Satoshi S Funabiki Kazuo K Hikida Takatoshi T
PloS one 20170712 7
A combination of genetically-encoded calcium indicators and micro-optics has enabled monitoring of large-scale dynamics of neuronal activity from behaving animals. In these studies, wide-field microscopy is often used to visualize neural activity. However, this method lacks optical sectioning capability, and therefore its axial resolution is generally poor. At present, it is unclear whether wide-field microscopy can visualize activity of densely packed small neurons at cellular resolution. To ex ...[more]