Ontology highlight
ABSTRACT:
SUBMITTER: Aranda-Diaz A
PROVIDER: S-EPMC5507677 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Aranda-Díaz Andrés A Mace Kieran K Zuleta Ignacio I Harrigan Patrick P El-Samad Hana H
ACS synthetic biology 20161227 3
Cellular phenotypes are the result of complex interactions between many components. Understanding and predicting the system level properties of the resulting networks requires the development of perturbation tools that can simultaneously and independently modulate multiple cellular variables. Here, we develop synthetic modules that use different arrangements of two transcriptional regulators to achieve either concurrent and independent control of the expression of two genes, or decoupled control ...[more]