Ontology highlight
ABSTRACT:
SUBMITTER: Ghurye J
PROVIDER: S-EPMC5508778 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Ghurye Jay J Pop Mihai M Koren Sergey S Bickhart Derek D Chin Chen-Shan CS
BMC genomics 20170712 1
<h4>Background</h4>Long read technologies have revolutionized de novo genome assembly by generating contigs orders of magnitude longer than that of short read assemblies. Although assembly contiguity has increased, it usually does not reconstruct a full chromosome or an arm of the chromosome, resulting in an unfinished chromosome level assembly. To increase the contiguity of the assembly to the chromosome level, different strategies are used which exploit long range contact information between c ...[more]