Ontology highlight
ABSTRACT:
SUBMITTER: Kumar R
PROVIDER: S-EPMC5509344 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Kumar Ritesh R Herold Jennifer L JL Schady Deborah D Davis Jennifer J Kopetz Scott S Martinez-Moczygemba Margarita M Murray Barbara E BE Han Fang F Li Yu Y Callaway Evelyn E Chapkin Robert S RS Dashwood Wan-Mohaiza WM Dashwood Roderick H RH Berry Tia T Mackenzie Chris C Xu Yi Y
PLoS pathogens 20170713 7
Streptococcus gallolyticus subsp. gallolyticus (Sg) has long been known to have a strong association with colorectal cancer (CRC). This knowledge has important clinical implications, and yet little is known about the role of Sg in the development of CRC. Here we demonstrate that Sg promotes human colon cancer cell proliferation in a manner that depends on cell context, bacterial growth phase and direct contact between bacteria and colon cancer cells. In addition, we observed increased level of β ...[more]