Ontology highlight
ABSTRACT:
SUBMITTER: Lowe DW
PROVIDER: S-EPMC5509506 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Lowe Danielle W DW Hollis Bruce W BW Wagner Carol L CL Bass Thomas T Kaufman David A DA Horgan Michael J MJ Givelichian Laurence M LM Sankaran Koravangatta K Yager Jerome Y JY Katikaneni Lakshmi D LD Wiest Don D Jenkins Dorothea D
Pediatric research 20170117 1
<h4>Background</h4>Vitamin D has neuroprotective and immunomodulatory properties, and deficiency is associated with worse stroke outcomes. Little is known about effects of hypoxia-ischemia or hypothermia treatment on vitamin D status in neonates with hypoxic-ischemic encephalopathy (HIE). We hypothesized vitamin D metabolism would be dysregulated in neonatal HIE altering specific cytokines involved in Th17 activation, which might be mitigated by hypothermia.<h4>Methods</h4>We analyzed short-term ...[more]