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Chitosan-Gated Magnetic-Responsive Nanocarrier for Dual-Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy.


ABSTRACT: A dual-layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on-demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic-thermal and chemotherapy.

SUBMITTER: Wang H 

PROVIDER: S-EPMC5510588 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Chitosan-Gated Magnetic-Responsive Nanocarrier for Dual-Modal Optical Imaging, Switchable Drug Release, and Synergistic Therapy.

Wang Hui H   Mu Qingxin Q   Revia Richard R   Wang Kui K   Zhou Xuezhe X   Pauzauskie Peter J PJ   Zhou Shuiqin S   Zhang Miqin M  

Advanced healthcare materials 20170125 6


A dual-layer shell hollow nanostructure as drug carrier that provides instant on/off function for drug release and contrast enhancement for multimodal imaging is reported. The on-demand drug release is triggered by irradiation of an external magnetic field. The nanocarrier also demonstrates a high drug loading capacity and synergistic magnetic-thermal and chemotherapy. ...[more]

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