Ontology highlight
ABSTRACT:
SUBMITTER: Brunstein CG
PROVIDER: S-EPMC5510875 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Brunstein Claudio G CG Cutler Corey S CS DeFor Todd E TE Kim Haesook H Bejanyan Nelli N Garfall Alfred A Verneris Michael R MR Chen Yi-Bin YB Warlick Erica D ED Spitzer Thomas T Miller Jeffrey S JS Antin Joseph H JH Weisdorf Daniel J DJ Soiffer Robert R Wagner John E JE Ballen Karen K KK
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20161029 1
We studied the effect of HLA-C matching in 515 patients after double umbilical cord blood (UCB) transplantation. After HLA matching HLA-A, -B, and -DRB1 at the allele level, we scored patients according to number of donor-recipient HLA-C matches at 4 possible loci: 2 from each donor unit, at the allele level. Given a direct interaction between HLA-A, -B, and -DRB1 matching and HLA-C score, we analyzed HLA-C matching in those receiving at least 1 2/6 to 4/6 HLA-matched unit (n = 389) versus those ...[more]