Ontology highlight
ABSTRACT:
SUBMITTER: Mehner C
PROVIDER: S-EPMC5511892 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Mehner Christine C Oberg Ann L AL Goergen Krista M KM Kalli Kimberly R KR Maurer Matthew J MJ Nassar Aziza A Goode Ellen L EL Keeney Gary L GL Jatoi Aminah A Radisky Derek C DC Radisky Evette S ES
Genes & cancer 20170501 5-6
<h4>Background</h4>Limited effectiveness of therapeutic agents targeting epidermal growth factor receptor (EGFR) in clinical trials using unselected ovarian cancer patients has prompted efforts to more effectively stratify patients who might best benefit from these therapies. A series of studies that have evaluated immunohistochemical (IHC) staining of EGFR in ovarian cancer biopsies has produced unclear results as to the utility of this measure as a prognostic biomarker. Here, we used one of th ...[more]