Ontology highlight
ABSTRACT:
SUBMITTER: Chew KS
PROVIDER: S-EPMC5513697 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Chew Kylie S KS Renna Jordan M JM McNeill David S DS Fernandez Diego C DC Keenan William T WT Thomsen Michael B MB Ecker Jennifer L JL Loevinsohn Gideon S GS VanDunk Cassandra C Vicarel Daniel C DC Tufford Adele A Weng Shijun S Gray Paul A PA Cayouette Michel M Herzog Erik D ED Zhao Haiqing H Berson David M DM Hattar Samer S
eLife 20170615
The visual system consists of two major subsystems, image-forming circuits that drive conscious vision and non-image-forming circuits for behaviors such as circadian photoentrainment. While historically considered non-overlapping, recent evidence has uncovered crosstalk between these subsystems. Here, we investigated shared developmental mechanisms. We revealed an unprecedented role for light in the maturation of the circadian clock and discovered that intrinsically photosensitive retinal gangli ...[more]