Pediatric obesity is associated with an altered gut microbiota and discordant shifts in Firmicutes populations.
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ABSTRACT:
SUBMITTER: Riva A
PROVIDER: S-EPMC5516186 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
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Pediatric obesity is associated with an altered gut microbiota and discordant shifts in Firmicutes populations.
Riva Alessandra A Borgo Francesca F Lassandro Carlotta C Verduci Elvira E Morace Giulia G Borghi Elisa E Berry David D
Environmental microbiology 20160822 1
An altered gut microbiota has been linked to obesity in adulthood, although little is known about childhood obesity. The aim of this study was to characterize the composition of the gut microbiota in obese (n = 42) and normal-weight (n = 36) children aged 6 to 16. Using 16S rRNA gene-targeted sequencing, we evaluated taxa with differential abundance according to age- and sex-normalized body mass index (BMI z-score). Obesity was associated with an altered gut microbiota characterized by elevated ...[more]
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