Cockroach allergen exposure and plasma cytokines among children in a tropical environment.

ABSTRACT:

Background

Little is known about the effects of socioeconomic status or cockroach allergen on immune responses in school-age children, particularly in tropical environments.

Objective

To examine whether cockroach allergen and/or socioeconomic status is associated with plasma cytokine levels in Puerto Rican children.

Methods

This was a cross-sectional study of 532 children (6-14 years old) with (n = 272) and without (n = 260) asthma in San Juan (Puerto Rico). House dust allergens (cockroach [Bla g 2], dust mite [Der p 1], cat dander [Fel d 1], dog dander [Can f 1], and mouse urinary protein [Mus m 1]) were quantified using monoclonal antibody arrays. A panel of 14 cytokines (interleukin [IL]-1β, IL-4, IL-6, IL-10, IL-17A, IL-17F, IL-21, IL-22, IL-23, IL-25, IL-31, IL-3

SUBMITTER: Medsker BH 

PROVIDER: S-EPMC5517099 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature