Ontology highlight
ABSTRACT:
SUBMITTER: Li X
PROVIDER: S-EPMC5517634 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Li Xiaoyan X Gu Yurong Y Guo Xiaobo X Gu Lin L Zhou Liang L Wu Xiaojuan X Wang Xueqin X Stamataki Zania Z Huang Yuehua Y
Scientific reports 20170719 1
Natural killer (NK) cells play a major role in anti-viral immunity as first line defense during hepatitis B infection, particularly in untreated patients whose T cells functions are profoundly impaired. Cytokine interferon (IFN)-γ and tumor necrosis factor (TNF)-α produced by NK cells are important anti-viral factors. However, there is lack of a quantifiable model to evaluate cytokine responses by NK cells. In this study, almost half of the patients (47.9%) beyond treatment criteria had high cyt ...[more]