Ontology highlight
ABSTRACT:
SUBMITTER: Smith SR
PROVIDER: S-EPMC5518190 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Smith Steven R SR Garvey W Timothy WT Greenway Frank L FL Zhou Sharon S Fain Randi R Pilson Robert R Fujioka Ken K Aronne Louis J LJ
Obesity (Silver Spring, Md.) 20170501 5
<h4>Objective</h4>To assess the short-term tolerability of lorcaserin alone or with two dose regimens of phentermine.<h4>Methods</h4>This was a 12-week, randomized, double-blind, pilot safety study of N = 238 nondiabetic patients with obesity or overweight with ≥1 comorbidity randomized to lorcaserin 10 mg twice daily (BID; LOR BID) alone or with phentermine 15 mg once daily (QD; LOR BID+PHEN QD) or 15 mg twice daily (LOR BID+PHEN BID). Patients reporting ≥ 1 of 9 potentially serotonergic advers ...[more]