Ontology highlight
ABSTRACT:
SUBMITTER: Vedeld HM
PROVIDER: S-EPMC5518206 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Vedeld Hege Marie HM Merok Marianne M Jeanmougin Marine M Danielsen Stine A SA Honne Hilde H Presthus Gro Kummeneje GK Svindland Aud A Sjo Ole H OH Hektoen Merete M Eknaes Mette M Nesbakken Arild A Lothe Ragnhild A RA Lind Guro E GE
International journal of cancer 20170602 5
The prognostic value of CpG island methylator phenotype (CIMP) in colorectal cancer remains unsettled. We aimed to assess the prognostic value of this phenotype analyzing a total of 1126 tumor samples obtained from two Norwegian consecutive colorectal cancer series. CIMP status was determined by analyzing the 5-markers CAGNA1G, IGF2, NEUROG1, RUNX3 and SOCS1 by quantitative methylation specific PCR (qMSP). The effect of CIMP on time to recurrence (TTR) and overall survival (OS) were determined b ...[more]