Ontology highlight
ABSTRACT:
SUBMITTER: Tatman PD
PROVIDER: S-EPMC5518568 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Tatman Philip D PD Woulfe Kathleen C KC Karimpour-Fard Anis A Jeffrey Danielle A DA Jaggers James J Cleveland Joseph C JC Nunley Karin K Taylor Matthew Rg MR Miyamoto Shelley D SD Stauffer Brian L BL Sucharov Carmen C CC
JCI insight 20170720 14
Our previous work showed myocellular differences in pediatric and adult dilated cardiomyopathy (DCM). However, a thorough characterization of the molecular pathways involved in pediatric DCM does not exist, limiting the development of age-specific therapies. To characterize this patient population, we investigated the transcriptome profile of pediatric patients. RNA-Seq from 7 DCM and 7 nonfailing (NF) explanted age-matched pediatric left ventricles (LV) was performed. Changes in gene expression ...[more]