Ontology highlight
ABSTRACT:
SUBMITTER: Yi Z
PROVIDER: S-EPMC5519668 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20170720 1
It is particularly important to provide precise therapies and understand tumor heterogeneity based on the molecular typing of mutational landscape. However, the landscape of somatic mutations in different subtypes of advanced breast cancer (ABC) is largely unknown. We applied target-region capture deep sequencing to determine the frequency and spectrum of common cancer-related gene mutations in circulating tumor DNA (ctDNA) among different ABC subtypes and analyze their association with clinical ...[more]