Unknown

Dataset Information

0

Diterpenoid Alkaloids from Delphinium anthriscifolium var. majus.


ABSTRACT: Extensive phytochemical investigation on the whole herbs of Delphinium anthriscifolium var. majus led to the identification of fourteen diterpenoid alkaloids, including three new C20-diterpenoid alkaloids (anthriscifolsines A-C, 1-3), six new C19-diterpenoid alkaloids (anthriscifolrines A-F, 4-9), and five know compounds (10-14). Among them, anthriscifolsine A represents a novel C20-diterpenoid alkaloid characterized by a seco C-ring. The structures of the isolated compounds were elucidated by extensive spectroscopic methods, including HR-ESI-MS, X-ray, and 1D and 2D NMR experiments. Bioactivity of compounds 3-6 was evaluated for their cytotoxicity against the MCF-7, HepG2 and H460 cancer cell lines.

SUBMITTER: Shan LH 

PROVIDER: S-EPMC5519776 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

Diterpenoid Alkaloids from Delphinium anthriscifolium var. majus.

Shan Lian-Hai LH   Zhang Ji-Fa JF   Gao Feng F   Huang Shuai S   Zhou Xian-Li XL  

Scientific reports 20170720 1


Extensive phytochemical investigation on the whole herbs of Delphinium anthriscifolium var. majus led to the identification of fourteen diterpenoid alkaloids, including three new C<sub>20</sub>-diterpenoid alkaloids (anthriscifolsines A-C, 1-3), six new C<sub>19</sub>-diterpenoid alkaloids (anthriscifolrines A-F, 4-9), and five know compounds (10-14). Among them, anthriscifolsine A represents a novel C<sub>20</sub>-diterpenoid alkaloid characterized by a seco C-ring. The structures of the isolat  ...[more]

Similar Datasets

| S-EPMC7961722 | biostudies-literature
| S-EPMC9325274 | biostudies-literature
| S-EPMC6474827 | biostudies-literature
| S-EPMC4374035 | biostudies-literature
| S-EPMC2977125 | biostudies-other
| S-EPMC9043348 | biostudies-literature
| S-EPMC6264398 | biostudies-literature
| S-EPMC6260597 | biostudies-literature
| S-EPMC8275754 | biostudies-literature
| S-EPMC6372304 | biostudies-literature