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Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.

ABSTRACT: Work-related cancer is an important public health issue with a large financial impact on society. The key European legislative instrument is the Carcinogens and Mutagens Directive (2004/37/EC). In preparation for updating the Directive, the European Commission commissioned a study to provide a socioeconomic, health and environmental impact assessment.The evaluation was undertaken for 25 preselected hazardous substances or mixtures. Estimates were made of the number of cases of cancer attributable to workplace exposure, both currently and in the future, with and without any regulatory interventions, and these data were used to estimate the financial health costs and benefits.It was estimated that if no action is taken there will be >700?000 attributable cancer deaths over the next 60 years for the substances assessed. However, there are only seven substances where the data suggest a clear benefit in terms of avoided cancer cases from introducing a binding limit at the levels considered. Overall, the costs of the proposed interventions were very high (up to [euro ]34?000 million) and the associated monetised health benefits were mostly less than the compliance costs.The strongest cases for the introduction of a limit value are for: respirable crystalline silica, hexavalent chromium, and hardwood dust.

SUBMITTER: Cherrie JW

PROVIDER: S-EPMC5520511 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.

Cherrie J W JW Hutchings S S Gorman Ng M M Mistry R R Corden C C Lamb J J Sánchez Jiménez A A Shafrir A A Sobey M M van Tongeren M M Rushton L L

British journal of cancer 20170613 2

<h4>Background</h4>Work-related cancer is an important public health issue with a large financial impact on society. The key European legislative instrument is the Carcinogens and Mutagens Directive (2004/37/EC). In preparation for updating the Directive, the European Commission commissioned a study to provide a socioeconomic, health and environmental impact assessment.<h4>Methods</h4>The evaluation was undertaken for 25 preselected hazardous substances or mixtures. Estimates were made of the nu ...[more]

PMID: 28609433

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Project description:ObjectivesThe Network on the Coordination and Harmonisation of European Occupational Cohorts (OMEGA-NET) was set up to enable optimization of the use of industrial and general population cohorts across Europe to advance aetiological research. High-quality harmonized exposure assessment is crucial to derive comparable results and to enable pooled analyses. To facilitate a harmonized research strategy, a concerted effort is needed to catalogue available occupational exposure information. We here aim to provide a first comprehensive overview of exposure assessment tools that could be used for occupational epidemiological studies.MethodsAn online inventory was set up to collect meta-data on exposure assessment tools. Occupational health researchers were invited via newsletters, editorials, and individual e-mails to provide details of job-exposure matrices (JEMs), exposure databases, and occupational coding systems and their associated crosswalks to translate codes between different systems, with a focus on Europe.ResultsMeta-data on 36 general population JEMs, 11 exposure databases, and 29 occupational coding systems from more than 10 countries have been collected up to August 2021. A wide variety of exposures were covered in the JEMs on which data were entered, with dusts and fibres (in 14 JEMs) being the most common types. Fewer JEMs covered organization of work (5) and biological factors (4). Dusts and fibres were also the most common exposures included in the databases (7 out of 11), followed by solvents and pesticides (both in 6 databases).ConclusionsThis inventory forms the basis for a searchable web-based database of meta-data on existing occupational exposure information, to support researchers in finding the available tools for assessing occupational exposures in their cohorts, and future efforts for harmonization of exposure assessment. This inventory remains open for further additions, to enlarge its coverage and include newly developed tools.

Dataset Information

Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.

Publications

Prioritising action on occupational carcinogens in Europe: a socioeconomic and health impact assessment.

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