Ontology highlight
ABSTRACT:
SUBMITTER: Chmielarz P
PROVIDER: S-EPMC5520729 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Chmielarz Piotr P Konovalova Julia J Najam Syeda Sadia SS Alter Heike H Piepponen Timo Petteri TP Erfle Holger H Sonntag Kai C KC Schütz Günther G Vinnikov Ilya A IA Domanskyi Andrii A
Cell death & disease 20170525 5
MicroRNAs (miRs) are important post-transcriptional regulators of gene expression implicated in neuronal development, differentiation, aging and neurodegenerative diseases, including Parkinson's disease (PD). Several miRs have been linked to PD-associated genes, apoptosis and stress response pathways, suggesting that deregulation of miRs may contribute to the development of the neurodegenerative phenotype. Here, we investigate the cell-autonomous role of miR processing RNAse Dicer in the functio ...[more]