Ontology highlight
ABSTRACT:
SUBMITTER: Park J
PROVIDER: S-EPMC5522104 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Park Jisook J Lee Eunjung E Park Kyoung-Jin KJ Park Hyung-Doo HD Kim Jong-Won JW Woo Hye In HI Lee Kwang Hyuck KH Lee Kyu-Taek KT Lee Jong Kyun JK Park Joon-Oh JO Park Young Suk YS Heo Jin Seok JS Choi Seong Ho SH Choi Dong Wook DW Jang Kee-Taek KT Lee Soo-Youn SY
Oncotarget 20170601 26
We performed an integrated analysis of proteomic and transcriptomic datasets to develop potential diagnostic markers for early pancreatic cancer. In the discovery phase, a multiple reaction monitoring assay of 90 proteins identified by either gene expression analysis or global serum proteome profiling was established and applied to 182 clinical specimens. Nine proteins (P < 0.05) were selected for the independent validation phase and quantified using stable isotope dilution-multiple reaction mon ...[more]