Ontology highlight
ABSTRACT:
SUBMITTER: Cosgarea I
PROVIDER: S-EPMC5522195 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Cosgarea Ioana I Ugurel Selma S Sucker Antje A Livingstone Elisabeth E Zimmer Lisa L Ziemer Mirjana M Utikal Jochen J Mohr Peter P Pfeiffer Christiane C Pföhler Claudia C Hillen Uwe U Horn Susanne S Schadendorf Dirk D Griewank Klaus G KG Roesch Alexander A
Oncotarget 20170601 25
<h4>Purpose</h4>Mucosal melanoma represents ~1% of all melanomas, frequently having a poor prognosis due to diagnosis at a late stage of disease. Mucosal melanoma differs from cutaneous melanoma not only in terms of poorer clinical outcome but also on the molecular level having e.g. less BRAF and more frequent KIT mutations than cutaneous melanomas. For the majority of mucosal melanomas oncogenic driver mutations remain unknown.<h4>Experimental design and results</h4>In our study, 75 tumor tissu ...[more]