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Distinct contributions by frontal and parietal cortices support working memory.

ABSTRACT: Although subregions of frontal and parietal cortex both contribute and coordinate to support working memory (WM) functions, their distinct contributions remain elusive. Here, we demonstrate that perturbations to topographically organized human frontal and parietal cortex during WM maintenance cause distinct but systematic distortions in WM. The nature of these distortions supports theories positing that parietal cortex mainly codes for retrospective sensory information, while frontal cortex codes for prospective action.

SUBMITTER: Mackey WE

PROVIDER: S-EPMC5522403 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Distinct contributions by frontal and parietal cortices support working memory.

Mackey Wayne E WE Curtis Clayton E CE

Scientific reports 20170721 1

Although subregions of frontal and parietal cortex both contribute and coordinate to support working memory (WM) functions, their distinct contributions remain elusive. Here, we demonstrate that perturbations to topographically organized human frontal and parietal cortex during WM maintenance cause distinct but systematic distortions in WM. The nature of these distortions supports theories positing that parietal cortex mainly codes for retrospective sensory information, while frontal cortex code ...[more]

PMID: 28733684

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