Effect of Digoxin Use Among Medicaid Enrollees With Atrial Fibrillation.

ABSTRACT:

Background

Recently published analysis of contemporary atrial fibrillation (AF) cohorts showed an association between digoxin and increased mortality and hospitalizations; however, other studies have demonstrated conflicting results. Many AF cohort studies did not or were unable to examine racial differences. Our goal was to examine risk factors for hospitalizations and mortality with digoxin use in a diverse real-world AF patient population and evaluate racial differences.

Methods and results

We performed a retrospective cohort analysis of claims data for Medicaid beneficiaries, aged 18 to 64 years, with incident diagnosis of AF in 2008 with follow-up until December 31, 2009. We created Kaplan-Meier curves and constructed multivariable Cox proportional hazard models for mor

SUBMITTER: Adedinsewo D 

PROVIDER: S-EPMC5522586 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature