DksA2, a zinc-independent structural analog of the transcription factor DksA.
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ABSTRACT:
SUBMITTER: Furman R
PROVIDER: S-EPMC5525025 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
DksA2, a zinc-independent structural analog of the transcription factor DksA.
Furman Ran R Biswas Tapan T Danhart Eric M EM Foster Mark P MP Tsodikov Oleg V OV Artsimovitch Irina I
FEBS letters 20130214 6
Transcription factor DksA contains a four-Cys Zn(2 +)-finger motif thought to be responsible for structural integrity and the relative disposition of its domains. Pseudomonas aeruginosa encodes an additional DksA paralog (DksA2) that is expressed selectively under Zn(2+) limitation. Although DksA2 does not bind Zn(2+), it complements the Escherichia coli dksA deletion and has similar effects on transcription in vitro. In this study, structural and biochemical analyses reveal that DksA2 has a sim ...[more]
Similar Datasets
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