Ontology highlight
ABSTRACT:
SUBMITTER: Deng L
PROVIDER: S-EPMC5526067 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Deng Lei L Kim Jong R JR Chang Timothy Z TZ Zhang Han H Mohan Teena T Champion Julie A JA Wang Bao-Zhong BZ
Virology 20170613
Currently marketed influenza vaccines only confer protection against matching influenza virus strains. The influenza A composition of these vaccines needs to be annually updated. Vaccines that target conserved epitopes of influenza viruses would in principle offer broad cross-protection against influenza A viruses. In our study, we investigated the specific immune responses and protective efficacy of protein nanoparticles based on fusion proteins of flagellin carrier linked to conserved influenz ...[more]