Validation of the XDP-MDSP rating scale for the evaluation of patients with X-linked dystonia-parkinsonism.

ABSTRACT: X-linked dystonia-parkinsonism(XDP) is a neurodegenerative disorder endemic to the Philippines. A rating scale was developed by the authors under the guidance of the Movement Disorder Society of the Philippines (MDSP) to assess XDP severity and progression, functional impact, and response to treatment in future clinical trials. Our main objective was to validate our new scale, the XDP-MDSP scale. The initial validation process included pragmatic testing to XDP patients followed by a modified Delphi procedure with an international advisory panel of dystonia, parkinsonism and scale development experts. Pearson correlation was used to assess construct validity of our new scale versus the assess construct validity of our new scale versus standard dystonia, parkinsonism, non-motor and functiona

SUBMITTER: Pasco PMD 

PROVIDER: S-EPMC5526880 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature