Ontology highlight
ABSTRACT:
SUBMITTER: Cienfuegos-Gallet AV
PROVIDER: S-EPMC5527652 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Cienfuegos-Gallet Astrid V AV Chen Liang L Kreiswirth Barry N BN Jiménez J Natalia JN
Antimicrobial agents and chemotherapy 20170725 8
Here we describe the spread of colistin resistance in clinical isolates of carbapenem-resistant <i>Klebsiella pneumoniae</i> in Medellín, Colombia. Among 32 isolates collected between 2012 and 2014, 24 showed genetic alterations in <i>mgrB</i> Nineteen isolates belonged to sequence type 512 (ST512) (or its single locus variant [SLV]) and harbored an 8.1-kb <i>hsdMSR</i> insertion corresponding to IS<i>Kpn25</i>, indicating a clonal expansion of the resistant strain. The insertion region showed 1 ...[more]