Ontology highlight
ABSTRACT:
SUBMITTER: Cerveira N
PROVIDER: S-EPMC5528393 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Cerveira Nuno N Lisboa Susana S Correia Cecília C Bizarro Susana S Santos Joana J Torres Lurdes L Vieira Joana J Barros-Silva João D JD Pereira Dulcineia D Moreira Cláudia C Meyer Claus C Oliva Tereza T Moreira Ilídia I Martins Ângelo  Viterbo Luísa L Costa Vítor V Marschalek Rolf R Pinto Armando A Mariz José M JM Teixeira Manuel R MR
Molecular oncology 20120714 5
Chromosomal rearrangements affecting the MLL gene are associated with high-risk pediatric, adult and therapy-associated acute leukemia. In this study, conventional cytogenetic, fluorescence in situ hybridization, and molecular genetic studies were used to characterize the type and frequency of MLL rearrangements in a consecutive series of 45 Portuguese patients with MLL-related leukemia treated in a single institution between 1998 and 2011. In the group of patients with acute lymphoblastic leuke ...[more]