Ontology highlight
ABSTRACT:
SUBMITTER: Tiziani S
PROVIDER: S-EPMC5529142 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Tiziani Stefano S Kang Yunyi Y Choi Janet S JS Roberts William W Paternostro Giovanni G
Nature communications 20111122
Metabolism is altered in many highly prevalent diseases and is controlled by a complex network of intracellular regulators. Monitoring cell metabolism during treatment is extremely valuable to investigate cellular response and treatment efficacy. Here we describe a nuclear magnetic resonance-based method for screening of the metabolomic response of drug-treated mammalian cells in a 96-well format. We validate the met ...[more]