Martini Coarse-Grained Force Field: Extension to RNA.
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ABSTRACT:
SUBMITTER: Uusitalo JJ
PROVIDER: S-EPMC5529176 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Martini Coarse-Grained Force Field: Extension to RNA.
Uusitalo Jaakko J JJ Ingólfsson Helgi I HI Marrink Siewert J SJ Faustino Ignacio I
Biophysical journal 20170617 2
RNA has an important role not only as the messenger of genetic information but also as a regulator of gene expression. Given its central role in cell biology, there is significant interest in studying the structural and dynamic behavior of RNA in relation to other biomolecules. Coarse-grain molecular dynamics simulations are a key tool to that end. Here, we have extended the coarse-grain Martini force field to include RNA after our recent extension to DNA. In the same way DNA was modeled, the te ...[more]
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