Ontology highlight
ABSTRACT:
SUBMITTER: Bell TM
PROVIDER: S-EPMC5530372 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Antiviral research 20170423
Despite over 60 years of research on antiviral drugs, very few are FDA approved to treat acute viral infections. Rift Valley fever virus (RVFV), an arthropod borne virus that causes hemorrhagic fever in severe cases, currently lacks effective treatments. Existing as obligate intracellular parasites, viruses have evolved to manipulate host cell signaling pathways to meet their replication needs. Specifically, translation modulation is often necessary for viruses to establish infection in their ho ...[more]