Ontology highlight
ABSTRACT:
SUBMITTER: Park KT
PROVIDER: S-EPMC5530704 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Park Kyung-Tae KT Villar Maria T MT Artigues Antonio A Lutkenhaus Joe J
Proceedings of the National Academy of Sciences of the United States of America 20170626 29
In <i>Escherichia coli</i> MinE induces MinC/MinD to oscillate between the ends of the cell, contributing to the precise placement of the Z ring at midcell. To do this, MinE undergoes a remarkable conformational change from a latent 6β-stranded form that diffuses in the cytoplasm to an active 4β-stranded form bound to the membrane and MinD. How this conformational switch occurs is not known. Here, using hydrogen-deuterium exchange coupled to mass spectrometry (HDX-MS) we rule out a model in whic ...[more]