Ontology highlight
ABSTRACT:
SUBMITTER: Pirini F
PROVIDER: S-EPMC5532520 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
International journal of environmental health research 20170201 1
We investigated if prenatal exposures to tobacco smoke lead to changes in mitochondrial DNA content (mtDNA) in cord serum and adversely affect newborns' health. Umbilical cord serum cotinine levels were used to determine in utero exposure to smoking. Cord serum mtDNA was measured by quantitative polymerase chain reaction analysis of the genes coding for cytochrome c oxidase1 (MT-CO1) and cytochrome c oxidase2 (MT-CO2). Log transformed levels of mtDNA coding for MT-CO1 and MT-CO2 were significant ...[more]