Ontology highlight
ABSTRACT:
SUBMITTER: Schreiber AM
PROVIDER: S-EPMC553331 | biostudies-literature | 2005 Mar
REPOSITORIES: biostudies-literature
Schreiber Alex M AM Cai Liquan L Brown Donald D DD
Proceedings of the National Academy of Sciences of the United States of America 20050228 10
Thyroid hormone controls remodeling of the tadpole intestine during the climax of amphibian metamorphosis. In 8 days, the Xenopus laevis tadpole intestine shortens in length by 75%. Simultaneously, the longitudinal muscle fibers contract by about the same extent. The radial muscle fibers also shorten as the diameter narrows. Many radial fibers undergo programmed cell death. We conclude that muscle remodeling and contraction play key roles in the shortening process. Shortening is accompanied by a ...[more]