Ontology highlight
ABSTRACT:
SUBMITTER: McKinley R
PROVIDER: S-EPMC5536784 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
McKinley Richard R Häni Levin L Gralla Jan J El-Koussy M M Bauer S S Arnold M M Fischer U U Jung S S Mattmann Kaspar K Reyes Mauricio M Wiest Roland R
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160101 8
Several clinical trials have recently proven the efficacy of mechanical thrombectomy for treating ischemic stroke, within a six-hour window for therapy. To move beyond treatment windows and toward personalized risk assessment, it is essential to accurately identify the extent of tissue-at-risk ("penumbra"). We introduce a fully automated method to estimate the penumbra volume using multimodal MRI (diffusion-weighted imaging, a T2w- and T1w contrast-enhanced sequence, and dynamic susceptibility c ...[more]