Ontology highlight
ABSTRACT:
SUBMITTER: Janel N
PROVIDER: S-EPMC5537644 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Janel N N Alexopoulos P P Badel A A Lamari F F Camproux A C AC Lagarde J J Simon S S Feraudet-Tarisse C C Lamourette P P Arbones M M Paul J L JL Dubois B B Potier M C MC Sarazin M M Delabar J M JM
Translational psychiatry 20170620 6
Early identification of Alzheimer's disease (AD) risk factors would aid development of interventions to delay the onset of dementia, but current biomarkers are invasive and/or costly to assess. Validated plasma biomarkers would circumvent these challenges. We previously identified the kinase DYRK1A in plasma. To validate DYRK1A as a biomarker for AD diagnosis, we assessed the levels of DYRK1A and the related markers brain-derived neurotrophic factor (BDNF) and homocysteine in two unrelated AD pa ...[more]