Characterization of Sudan Ebolavirus infection in ferrets.
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ABSTRACT:
SUBMITTER: Kroeker A
PROVIDER: S-EPMC5542265 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Characterization of Sudan Ebolavirus infection in ferrets.
Kroeker Andrea A He Shihua S de La Vega Marc-Antoine MA Wong Gary G Embury-Hyatt Carissa C Qiu Xiangguo X
Oncotarget 20170701 28
Sudan virus (SUDV) outbreaks in Africa are highly lethal; however, the development and testing of novel antivirals and vaccines for this virus has been limited by a lack of suitable animal models. Non-human primates (NHP) remain the gold standard for modeling filovirus disease, but they are not conducive to screening large numbers of experimental compounds and should only be used to test the most promising candidates. Therefore, other smaller animal models are a valuable asset. We have recently ...[more]
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