Ontology highlight
ABSTRACT:
SUBMITTER: Trillo P
PROVIDER: S-EPMC5542752 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Trillo Paz P Slagbrand Tove T Tinnis Fredrik F Adolfsson Hans H
ChemistryOpen 20170703 4
The development of a protocol for the reductive functionalization of amides into <i>N</i>-sulfonylformamidines is reported. The one-pot procedure is based on a mild catalytic reduction of tertiary amides into the corresponding enamines by the use of Mo(CO)<sub>6</sub> (molybdenum hexacarbonyl) and TMDS (1,1,3,3-tetramethyldisiloxane). The formed enamines were allowed to react with sulfonyl azides to give the target compounds in moderate to good yields. ...[more]