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[Use of lumbar puncture in the evaluation of late-onset sepsis in low birth weight neonates].

ABSTRACT: The objective of this study was to analyze the use of lumbar punctures (LP) in the evaluation of late-onset neonatal sepsis. It is recommended to perform an LP as part of the evaluation of late-onset sepsis. We used a cohort of 414 newborns with a birth weight <2000g in three hospitals in Lima. A LP was performed in 45/214 (21.0%) of sepsis evaluations and in 13/48 (27.1%) of culture-proven sepsis. Meningitis was diagnosed in 8/214 (3.7%) of the episodes and 8/45 (17.5%) of the evaluations that included an LP. The duration of treatment of the sepsis episodes without a LP and the episodes with a negative LP was similar, and shorter than the episodes with a positive LP. The use of LP in the evaluation of late-onset sepsis is low and can result in undiagnosed and undertreated meningitis. The use of LP in the evaluation of neonatal sepsis must be encouraged in the neonatal units.

SUBMITTER: Zea-Vera A 

PROVIDER: S-EPMC5544347 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature

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[Use of lumbar puncture in the evaluation of late-onset sepsis in low birth weight neonates].

Zea-Vera Alonso A   Turín Christie Gloria CG   Rueda María Susana MS   Guillén-Pinto Daniel D   Medina-Alva Pilar P   Tori Aldredo A   Rivas María M   Zegarra Jaime J   Castañeda Anne A   Cam Luis L   Ochoa Theresa J TJ  

Revista peruana de medicina experimental y salud publica 20160601 2

The objective of this study was to analyze the use of lumbar punctures (LP) in the evaluation of late-onset neonatal sepsis. It is recommended to perform an LP as part of the evaluation of late-onset sepsis. We used a cohort of 414 newborns with a birth weight <2000g in three hospitals in Lima. A LP was performed in 45/214 (21.0%) of sepsis evaluations and in 13/48 (27.1%) of culture-proven sepsis. Meningitis was diagnosed in 8/214 (3.7%) of the episodes and 8/45 (17.5%) of the evaluations that  ...[more]

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