Ontology highlight
ABSTRACT:
SUBMITTER: Rojo Romanos T
PROVIDER: S-EPMC5544745 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Rojo Romanos Teresa T Pladevall-Morera David D Langebeck-Jensen Kasper K Hansen Stine S Ng Leelee L Pocock Roger R
Scientific reports 20170804 1
Development of complex nervous systems requires precisely controlled neurogenesis. The generation and specification of neurons occur through the transcriptional and post-transcriptional control of complex regulatory networks. In vertebrates and invertebrates, the proneural basic-helix-loop-helix (bHLH) family of transcription factors has multiple functions in neurogenesis. Here, we identified the LIN-32/Atonal bHLH transcription factor as a key regulator of URXL/R oxygen-sensing neuron developme ...[more]