Ontology highlight
ABSTRACT:
SUBMITTER: Braymer JJ
PROVIDER: S-EPMC5546016 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Braymer Joseph J JJ Lill Roland R
The Journal of biological chemistry 20170614 31
The biogenesis of iron-sulfur (Fe/S) proteins in eukaryotes is a multistage, multicompartment process that is essential for a broad range of cellular functions, including genome maintenance, protein translation, energy conversion, and the antiviral response. Genetic and cell biological studies over almost 2 decades have revealed some 30 proteins involved in the synthesis of cellular [2Fe-2S] and [4Fe-4S] clusters and their incorporation into numerous apoproteins. Mechanistic aspects of Fe/S prot ...[more]