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Chimpanzee genomic diversity reveals ancient admixture with bonobos.


ABSTRACT: Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 years ago, probably with subsequent spread into Nigeria-Cameroon chimpanzees. Together with another, possibly more recent contact (after 200,000 years ago), bonobos contributed less than 1% to the central chimpanzee genomes. Admixture thus appears to have been widespread during hominid evolution.

SUBMITTER: de Manuel M 

PROVIDER: S-EPMC5546212 | biostudies-literature | 2016 Oct

REPOSITORIES: biostudies-literature

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Chimpanzee genomic diversity reveals ancient admixture with bonobos.

de Manuel Marc M   Kuhlwilm Martin M   Frandsen Peter P   Sousa Vitor C VC   Desai Tariq T   Prado-Martinez Javier J   Hernandez-Rodriguez Jessica J   Dupanloup Isabelle I   Lao Oscar O   Hallast Pille P   Schmidt Joshua M JM   Heredia-Genestar José María JM   Benazzo Andrea A   Barbujani Guido G   Peter Benjamin M BM   Kuderna Lukas F K LF   Casals Ferran F   Angedakin Samuel S   Arandjelovic Mimi M   Boesch Christophe C   Kühl Hjalmar H   Vigilant Linda L   Langergraber Kevin K   Novembre John J   Gut Marta M   Gut Ivo I   Navarro Arcadi A   Carlsen Frands F   Andrés Aida M AM   Siegismund Hans R HR   Scally Aylwyn A   Excoffier Laurent L   Tyler-Smith Chris C   Castellano Sergi S   Xue Yali Y   Hvilsom Christina C   Marques-Bonet Tomas T  

Science (New York, N.Y.) 20161027 6311


Our closest living relatives, chimpanzees and bonobos, have a complex demographic history. We analyzed the high-coverage whole genomes of 75 wild-born chimpanzees and bonobos from 10 countries in Africa. We found that chimpanzee population substructure makes genetic information a good predictor of geographic origin at country and regional scales. Multiple lines of evidence suggest that gene flow occurred from bonobos into the ancestors of central and eastern chimpanzees between 200,000 and 550,0  ...[more]

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