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Desmopressin use for minimising perioperative blood transfusion.


ABSTRACT:

SUBMITTER: Desborough MJ 

PROVIDER: S-EPMC5546394 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Desmopressin use for minimising perioperative blood transfusion.

Desborough Michael J MJ   Oakland Kathryn K   Brierley Charlotte C   Bennett Sean S   Doree Carolyn C   Trivella Marialena M   Hopewell Sally S   Stanworth Simon J SJ   Estcourt Lise J LJ  

The Cochrane database of systematic reviews 20170710


<h4>Background</h4>Blood transfusion is administered during many types of surgery, but its efficacy and safety are increasingly questioned. Evaluation of the efficacy of agents, such as desmopressin (DDAVP; 1-deamino-8-D-arginine-vasopressin), that may reduce perioperative blood loss is needed.<h4>Objectives</h4>To examine the evidence for the efficacy of DDAVP in reducing perioperative blood loss and the need for red cell transfusion in people who do not have inherited bleeding disorders.<h4>Se  ...[more]

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