Ontology highlight
ABSTRACT:
SUBMITTER: Kumar P
PROVIDER: S-EPMC5548413 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Kumar Parveen P Munnangi Prathyusha P Chowdary Kvs Rammohan KR Shah Varun J VJ Shinde Swapnil R SR Kolli Nanci R NR Halehalli Rachita R RR Nagarajaram Hampapathalu A HA Maddika Subbareddy S
Journal of proteome research 20170718 8
Tyrosine phosphatases play a critical role in many cellular processes and pathogenesis, yet comprehensive analysis of their functional interacting proteins in the cell is limited. By utilizing a proteomic approach, here we present an interaction network of 81 human tyrosine phosphatases built on 1884 high-confidence interactions of which 85% are unreported. Our analysis has linked several phosphatases with new cellular processes and unveiled protein interactions genetically linked to various hum ...[more]