Dopaminergic Medication Increases Reliance on Current Information in Parkinson's Disease.
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ABSTRACT:
SUBMITTER: Vilares I
PROVIDER: S-EPMC5549845 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Dopaminergic Medication Increases Reliance on Current Information in Parkinson's Disease.
Vilares Iris I Kording Konrad P KP
Nature human behaviour 20170717 8
The neurotransmitter dopamine is crucial for decision-making under uncertainty but its computational role is still a subject of intense debate. To test potential roles, we had patients with Parkinson's disease (PD), who have less internally-generated dopamine, participate in a visual decision-making task in which uncertainty in both prior and current sensory information was varied and where behavior is often predicted by Bayesian statistics. We found that many aspects of uncertainty processing w ...[more]
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